//开启Excel APP
            Excel.Application xlApp = new Excel.Application();

//获取程序下bin—>debug下的文件夹的两种方法(System.IO.Directory.GetCurrentDirectory()；System.AppDomain.CurrentDomain.BaseDirectory )

//读取模板

sTemplateFilePath = System.IO.Directory.GetCurrentDirectory() + "\\ExcelTempFile\\直通率.xlsx";

 //开启模板档案
            Excel.Workbook xlBook = xlApp.Workbooks.Open(sTemplateFilePath, Type.Missing, Type.Missing, Type.Missing
                                                , Type.Missing, Type.Missing, Type.Missing, Type.Missing
                                                , Type.Missing, Type.Missing, Type.Missing, Type.Missing
                                                , Type.Missing, Type.Missing, Type.Missing);

 //取得模板的sheets页面用于写入数据
                        Excel.Worksheet RtySheet= (Excel.Worksheet)xlBook.Worksheets["SheetTemp1"];

// Excel.Range oRange1 =RtySheet.get_Range() 用于取得excel中的区域

对excel列是用第一行的字母加第一列的序号来取得位置的；

具体想获取操作的代码可用宏录制；

c#操作excel的一些记录