/// <summary>
    /// 程序托盘区图标位置
    /// </summary>
    public class IconInfo
    {
        /// <summary>
        /// 托盘区句柄
        /// </summary>
        public IntPtr hWnd = IntPtr.Zero;
        /// <summary>
        /// 图标X坐标
        /// </summary>
        public int X;
        /// <summary>
        /// 图标Y坐标
        /// </summary>
        public int Y;
        /// <summary>
        /// 图标宽度
        /// </summary>
        public int Width;
        /// <summary>
        /// 图标高度
        /// </summary>
        public int Height;
        public bool InIconRect(Point p)
        {
            if (p.X >= X && p.X <= X + Width && p.Y >= Y && p.Y <= Y + Height)
            {
                return true;
            }
            return false;
        }
    }

在图标的MouseMove事件中加入，用来确定图标位置信息

        GetIconInfo();
<pre name="code" class="csharp">        //获取图标位置信息
        private void GetIconInfo()
        {
            Point p = Cursor.Position;
            MyIcon.hWnd = WindowFromPoint(p);
            int BtnSize = SendMessage(MyIcon.hWnd, TB_GETBUTTONSIZE, IntPtr.Zero, IntPtr.Zero);
            MyIcon.Width = BtnSize & 0xFFFF;
            MyIcon.Height = (BtnSize / 0x10000) & 0xFFFF;
            Rect rect = new Rect();
            if (GetWindowRect(MyIcon.hWnd, out rect))
            {
                if (MyIcon.Width != 0 && MyIcon.Height != 0)
                {
                    MyIcon.X = (p.X - rect.Left - py) / MyIcon.Width * MyIcon.Width + rect.Left + py;
                    MyIcon.Y = (p.Y - rect.Top - py) / MyIcon.Height * MyIcon.Height + rect.Top + py;
                }
            }
        }

        /// <summary>
        /// 不同操作系统偏移量
        /// </summary>
        private int py = 0;

        private const int WM_USER = 0x400;
        private const int TB_GETBUTTONSIZE = WM_USER + 58;
        private const int WM_SYSCOMMAND = 0x112;
        private const long SC_MINIMIZE = 0xF020;
        private const int WM_MOUSEMOVE = 0X0200;
        [DllImport("user32.dll")]
        public static extern int SendMessage(IntPtr hwnd, int wMsg, IntPtr wParam, IntPtr lParam);
        [DllImport("user32.dll")]
        private static extern bool GetWindowRect(IntPtr hwnd, out Rect lpRect);
        [DllImport("User32.dll")]
        private static extern IntPtr WindowFromPoint(Point p);
        /// <summary>
        /// 图标信息
        /// </summary>
        private IconInfo MyIcon = new IconInfo();

        // WIN7之后的系统有两像素偏移量 程序load时加入以下代码
            OperatingSystem os = Environment.OSVersion;
            if (os.Platform == PlatformID.Win32NT && os.Version.Major >= 6)
            {
                py = 2;
            }

C#判断鼠标是否在自己程序的NotifyIcon上