try

{

    string appPath = "\"" + Application.ExecutablePath + "\" \"%1\"";

    string strKey = Application.ProductName;

    string strKey_shell_open_cmd = strKey + @"\shell\open\command";

    var subKey = Registry.ClassesRoot.CreateSubKey(strKey);

    subKey.SetValue("URL Protocol", "1");

    var subKey_shell_open_cmd = Registry.ClassesRoot.CreateSubKey(strKey_shell_open_cmd);

    subKey_shell_open_cmd.SetValue(null, appPath);

}

catch (Exception ex)

{

    MessageBox.Show(string.Format("Web启动参数设置失败, 原因: {0}", ex.Message));

}