1. using System;
2. using System.Collections.Generic;
3. using System.Text;
4. //先添加引用
5. using Microsoft.Office.Interop.Excel;
6. using System.IO;
7. using System.Reflection;
8.  
9. namespace SighExcel
10. {
11.     public class Sign
12.     {
13.         /// <summary>
14.         /// 对Excel指定单元格进行操作
15.         /// </summary>
16.         /// <param name="filePath">EXCEL表格所′在路径</param>
17.         /// <param name="row">行号</param>
18.         /// <param name="column">列号</param>
19.         /// <param name="code">内容</param>
20.         /// <returns></returns>
21.         public bool signExcel(string filePath,int row, int column,string code)
22.         {
23.             try
24.             {
25.                 _Application excelApp = new Application();
26.                 Workbook wBook = excelApp.Workbooks.Open(filePath, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing, Type.Missing);
27.                 Worksheet wSheet = (Worksheet)wBook.Worksheets[1];
28.                 wSheet.Cells[row, column] = code;
29.                 Microsoft.Office.Interop.Excel.Range rtemp = wSheet.Range[wSheet.Cells[3, 4], wSheet.Cells[3, 6]];
30.                 rtemp.Font.Name="宋体";
31.                 rtemp.Font.Size=12;
32.                 object SaveChanges = XlSaveAction.xlDoNotSaveChanges;
33.                 wBook.Save();
34.                 wBook.Close();
35.                 excelApp.Quit();
36.                 return true;
37.             }
38.             catch (Exception e)
39.             {
40.                 System.IO.File.AppendAllText(System.IO.Path.Combine(GetCurrentPath(), "signExcellog.txt"), "文件" + filePath + "签入编号失败！错误:" + e.Message.ToString() + "。" + DateTime.Now.ToString("yyyy-MM-dd-hh:mm:ss"));
41.                 return false;
42.             }
43.         }
44.         /// <summary>
45.         ///得到当前程序的路径
46.         /// </summary>
47.         /// <returns></returns>
48.         static public string GetCurrentPath()
49.         {
50.             string asstring = Assembly.GetExecutingAssembly().Location;
51.             string[] aa = asstring.Split(‘\\‘);
52.             string path = string.Empty;
53.             foreach (string var in aa)
54.             {
55.                 if (var != aa[aa.Length - 1])
56.                     path += var + @"\";
57.             }
58.             return path;
59.         }
60.     }
61. }

C#实现对EXCEL指定单元格进行操作