因为官方的http://wiki.wxpython.org/InstallingOnUbuntuOrDebian 并没有wheezy的

所以这里我们直接去仓库搜吧

root@debian:/# apt-cache search python-wxgtk
python-wxgtk2.8 - wxWidgets Cross-platform C++ GUI toolkit (wxPython binding)
python-wxgtk2.8-dbg - wxWidgets Cross-platform C++ GUI toolkit (wxPython binding, debug version)

root@debian:/# apt-get install python
Display all 1846 possibilities? (y or n)
root@debian:/# apt-get install python-wxgtk2.8
Reading package lists... Done
Building dependency tree       
Reading state information... Done
The following package was automatically installed and is no longer required:
  libgadu3
Use 'apt-get autoremove' to remove it.
The following extra packages will be installed:
  python-wxversion
Suggested packages:
  wx2.8-doc wx2.8-examples editra
The following NEW packages will be installed:
  python-wxgtk2.8 python-wxversion
0 upgraded, 2 newly installed, 0 to remove and 0 not upgraded.
Need to get 8,671 kB of archives.
After this operation, 33.8 MB of additional disk space will be used.

现在写个简单的Hello world测试下吧

#!/usr/bin/env python
# coding=utf-8
import wx
app = wx.App(False)
frame = wx.Frame(None, wx.ID_ANY, "Hello World!")
frame.Show(True)
app.MainLoop()

debian(wheezy)安装wxPython进行GUI开发.