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homeostasis稳态
glucose 葡萄糖 |
健康食物让血糖变化小,不会像碳酸饮料,让血糖波动太大
目 录
1概述
2拓展意义
3内环境的稳态
4术语
5内环境稳态的概念
6其他相关
1概述
2拓展意义
3内环境的稳态
4术语
5内环境稳态的概念
内环境稳态与人体生理关系(生物必修三)[1]
Homeostasis — also spelled homoeostasis or homœostasis (from Greek: ?μοιος, "hómoios", "similar",[1] and στ?σις, stásis, "standing still"[2]) — is the property of a system in which variables are regulated so that internal conditions remain stable and relatively constant. Examples of homeostasis include the regulation of temperature and the balance between acidity and alkalinity (pH). It is a process which maintains the stability of the human body‘s internal environment in response to changes in external conditions.在一个系统内,各个变量有条不絮,内部环境稳定,持续,例如体温和ph值。
The concept was described by Claude Bernard in 1865 and the word was coined by Walter Bradford Cannon in 1926,[3] 1929[4] and 1932.[5][6] Although the term was originally used to refer to processes within living organisms, it is frequently applied to automatic control systems such as thermostats恒温器. Homeostasis requires a sensor to detect changes in the condition to be regulated, an effector mechanism which can vary that condition; and a negative feedbackconnection between the two.
Contents
[hide]- 1 Examples from technology
- 2 Biological
- 2.1 Control mechanisms
- 2.1.1 Negative feedback
- 2.2 Homeostatic imbalance
- 2.1 Control mechanisms
- 3 Ecological
- 4 Biosphere
- 5 Reactive
- 6 Other fields
- 6.1 Risk
- 6.2 Stress
- 7 Psychological
- 8 See also
- 9 References
- 10 Further reading
- 11 External links
Examples from technology[edit]
The following are all examples of familiar homeostatic mechanisms:
- A Thermostat operates by switching heaters or air-conditioners on and off in response to the output of a temperature sensor.
- Cruise control adjusts a car‘s throttle in response to changes in speed.
- An Autopilot operated the steering controls of an aircraft or ship in response to deviation from a pre-set compass bearing or route.
- Process control systems in a chemical plant or oil refinery maintain fluid levels, pressures, temperature, chemical composition, etc. by controlling heaters, pumps and valves.
- The centrifugal governor of a steam engine, as designed by James Watt in 1788, reduces the throttle valve in response to increases in the engine speed, or opens the valve if the speed falls below the pre-set rate.
Biological[edit]
All living organisms depend on maintaining a complex set of interacting metabolic chemical reactions. From the simplest single-celled organisms to the most complex plants and animals, internal processes operate to keep the conditions within tight limits to allow these reactions to proceed. Homeostatic processes act at the level of the cell, the tissue, theorgan, as well as for the organism as a whole.所有生物存活依靠复杂化学新陈代谢系统
Principal Homeostatic processes include the following:
- "Warm blooded" (endothermic) animals (mammals and birds) maintain a constant body temperature, while ectothermic animals (almost all other organisms) exhibit 表现wide bodytemperature variation巨大温差变化. [7] An advantage of temperature regulation is that it allows anorganism to function effectively in a broad range of environmental conditions. For example,ectotherms tend to become sluggish 迟缓的at low temperatures, whereas a co-located endotherm may be fully active. That thermal stability comes at a price since an automatic regulation system requires additional energy.[8] If the temperature rises, the body loses heat by sweating or panting喘气, via the latent heat of evaporation. If it falls, this is counteracted 对抗,抵消by increased metabolic action, by shivering, and - in fur- or feather-coated creatures - by thickening the coat.热血(内温)动物(哺乳动物和鸟类保持恒定体温),外温(冷血)动物体温变化很大.在各种环境下,一个高级温度调节可以让有机物有效工作。例如冷血动物在低温下,行为迟缓,外温动物可以完全发挥。高级温度调节机制需要消耗额外能量。如果温度上升,身体流汗或喘气散发热量。
- Regulation of the pH of the blood at 7.365 (a measure of alkalinity 碱度,碱性and acidity).人血液的恒定ph值是7.365
- All animals also regulate their blood glucose萄糖concentration血糖浓度. Mammals regulate their blood glucose with insulin 胰岛素and glucagon胰高血糖素. The human body maintains glucose levels constant most of the day, even after a 24-hour fast. Even during long periods of fasting, glucose levels are reduced only very slightly.[9] Insulin, secreted by the beta cells β细胞 f the pancreas胰, effectively transports glucose to the body‘s cells by instructing those cells to keep more of the glucose for their own use (see Dynamic equilibrium). If the glucose inside the cells is high, the cells will convert it to the insoluble glycogen to prevent the soluble glucose from interfering with cellular metabolism. Ultimately this lowers blood glucose levels, and insulin helps to preventhyperglycemia. When insulin is deficient or cells become resistant to it, diabetes occurs.当胰岛素缺乏或膝部产生抗体,糖尿病发生。 Glucagon, secreted by the alpha cells of the pancreas, encourages cells to break down stored glycogen or convert non-carbohydrate carbon sources to glucose via gluconeogenesis, thus preventing hypoglycemia.
- The kidneys are used to remove excess water and ions from the blood.肾用于移除血液里多余水和离子 These are then expelled as urine就像尿液方式排出体外. The kidneys perform a vital role in homeostatic regulation in mammals, removing excess water, salt, and urea尿素 from the blood.肾在稳态中极为重要,它能移除多余水,盐,尿素。(排尿原因)
- If the water content of the blood and lymph淋巴 fluid falls, it is restored in the first instance by extracting water from the cells. The throat and mouth become dry, so that the symptoms of thirst motivate the animal to drink.如果血液和淋巴液的水分流出,将从细胞提取水分,口腔咽喉干燥,就会出现口渴状态,然后去喝水。(口渴原因)
- If the oxygen content of the blood falls, or the carbon-dioxide concentration increases, blood flow is increased by more vigorous heart action and the speed and depth of breathing increases.
- Sleep timing depends upon a balance between homeostatic sleep propensity倾向,习性,癖好,偏爱 ,he need for sleep as a function of the amount of time elapsed since the last adequate sleep episode时期, and circadian rhythms
昼夜节律that determine the ideal timing of a correctly structured and restorative有恢复健康作用的sleep episode.
睡眠事件取决于一个平衡,即稳态的睡眠偏好和昼夜节律之间平衡。稳态的睡眠偏好是自从最近的睡眠时期,他需要睡眠的时间。昼夜节律决定了正确的和有恢复作用的睡眠时间框架。今天翻译了稳态,明白了熬夜就是慢性自杀。熬夜破坏了稳态,稳态破坏后人生命会有危险。
Control mechanisms控制机制[edit]
All homeostatic control mechanisms have at least three interdependent 互相依靠的components for the variable being regulated: The receptor is the sensing component that monitors and responds to changes in the environment. When the receptor senses a stimulus刺激物, it sends information to a "control center", the component that sets the range at which a variable is maintained. The control center determines an appropriate response to the stimulus. The control center then sends signals to an effector受动器;感受器
, which can be muscles, organs or other structures that receive signals from the control center. After receiving the signal, a change occurs to correct the deviation偏离;by depressing 压低it with negative feedback.
为了变量可以被调节,所有稳态控制机制有至少三个互相依靠的成分。接收器是一个感应成分,它可以监控和回应环境的变化。当接收器感应到刺激物,就会把信息传输到控制中心。控制中心负责设置变量值可取范围。针对刺激物,控制中心决定一个合适回应。控制中心发送信号到感受器。感受器可以是肌肉,器官,或者能够从控制中心接收信号的结构。接收器收到信号后,依靠negativefeedback 压低它,矫正偏差.Control mechanisms中,大脑充当控制中心角色。就是说大脑存储一个字典dict,字典的keys是身体各个器官,values是器官活动正常值范围。大脑是所有器官的枢纽中心,例如血压升高,血管会把信息传递给大脑,大脑决定一个合理值(心脏速度减慢)传递给心脏,心脏跳动减慢后,血压恢复正常,达到人体稳态。
2组成
反馈控制系统
负反馈
正反馈
反馈控制系统由控制器、受控对象和反馈通路组成。在反馈控制系统中,不管出于什么原因(外部扰动或系统内部变化),只要被控制量偏离规定值,就会产生相应的控制作用去消除偏差。因此,它具有抑制干扰的能力,对元件特性变化不敏感,并能改善系统的响应特性。
Negative feedback[edit]
Negative feedback mechanisms consist of reducing the output or activity of any organ or system back to its normal range of functioning. A good example of this is regulating blood pressure. Blood vessels can sense resistance of blood flow against the walls when blood pressure increases. The blood vessels act as the receptors and they relay this message to thebrain. The brain then sends a message to the heart and blood vessels, both of which are the effectors. The heart rate would decrease as the blood vessels increase in diameter 直径(known asvasodilation). This change would cause the blood pressure to fall back to its normal range. The opposite would happen when blood pressure decreases, and would cause vasoconstriction.
负反馈机制用于减少输出或活动。活动是任何器官或系统的正常发挥范围。例子,血压,血压升高后,血管能感应血流对墙的抗体。血管充当接收器,把信号传递给大脑。大脑发送信号到心脏和血管(接受器)。血管心脏跳动速度就会降低。心脏跳动速度改变会让血压返回到正常值。相反,如果血压降低,血管会收缩。
Another important example is seen when the body is deprived of food. The body would then reset the metabolic set point to a lower than normal value. This would allow the body to continue to function, at a slower rate, even though the body is starving. Therefore, people who deprive themselves of food while trying to lose weight would find it easy to shed weight initially and much harder to lose more after. This is due to the body readjusting itself to a lower metabolic set point to allow the body to survive with its low supply of energy. Exercise can change this effect by increasing the metabolic demand.另一个例子是禁食。人体重新设置新陈代谢值(低于正常值)。这会导致尽管饥饿,人体以较低节奏继续活动。我们用节食方式减肥,起初效果很明显,到后来效果越来越差。因为人体可以自动调节自身,当供应能量减少后,人体以一个较低新陈代谢速度继续存活。运动后,新陈代谢加快,改变这个效果。同时节食和运动,减肥效果并不好???
Another good example of negative feedback mechanism is temperature control. The hypothalamus, which monitors the body temperature, is capable of determining even the slightest variation of normal body temperature (37 degrees Celsius). Response to such variation could be stimulation of glands that produce sweat to reduce the temperature or signaling various muscles to shiver to increase body temperature.
Both feedbacks are equally important for the healthy functioning of one‘s body. Complications can arise if any of the two feedbacks are affected or altered in any way.
Homeostatic imbalance[edit]
Many diseases involve a disturbance of homeostasis.
As the organism ages, the efficiency in its control systems becomes reduced. The inefficiencies gradually result in an unstable internal environment that increases the risk of illness, and leads to the physical changes associated with aging.[11]
Certain homeostatic imbalances, such as high core temperature, a high concentration of salt in the blood, or low concentration of oxygen, can generate homeostatic emotions (such as warmth, thirst or breathlessness) which motivate behavior aimed at restoring homeostasis (such as removing a sweater, drinking or slowing down).[12]
Ecological[edit]
The concept of homeostasis is central to the topic of Ecological Stoichiometry. There it refers to the relationship between the chemical composition of an organism and the chemical composition of the nutrients it consumes. Stoichiometric homeostasis helps explain nutrient recycling and population dynamics.
Historically, ecological succession was seen as having a stable end-stage called the climax(see Frederic Clements), sometimes referred to as the ‘potential biodiversity‘ of a site, shaped primarily by the local climate. This idea has been largely abandoned by modern ecologists in favor of nonequilibrium ideas of how ecosystems function, as most natural ecosystems experience disturbance at a rate that makes a "climax" community unattainable.
Only on small, isolated habitats known as ecological islands can the phenomenon be observed. One such case study is the island of Krakatoa after its major eruption in 1883: the established stable homeostasis of the previous forest climax ecosystem was destroyed, and all life was eliminated from the island. In the years after the eruption, Krakatoa went through a sequence of ecological changes in which successive groups of new plant or animal species followed one another, leading to increasing biodiversity and eventually culminating in a re-established climax community. This ecological succession on Krakatoa occurred in a number of stages; a sere is defined as "a stage in a sequence of events by which succession occurs". The complete chain of seres leading to a climax is called a prisere. In the case of Krakatoa, the island reached its climax community, with eight hundred different recorded species, in 1983, one hundred years after the eruption that cleared all life off the island. Evidence confirms that this number has been homeostatic for some time, with the introduction of new species rapidly leading to elimination of old ones. The evidence of Krakatoa, and other disturbed island ecosystems, has confirmed many principles of Island Biogeography, mimicking general principles of ecological succession albeit in a virtually closed system comprised almost exclusively of endemic species.
Biosphere[edit]
In the Gaia hypothesis, James Lovelock stated that the entire mass of living matter on Earth (or any planet with life) functions as a vast homeostatic superorganism that actively modifies its planetary environment to produce the environmental conditions necessary for its own survival. In this view, the entire planet maintains homeostasis. Whether this sort of system is present on Earth is still open to debate. However, some relatively simple homeostatic mechanisms are generally accepted. For example, it is sometimes claimed that when atmospheric carbon dioxide levels rise, certain plants are able to grow better and thus act to remove more carbon dioxide from the atmosphere[dubious – discuss]. However, warming has exacerbated droughts, making water the actual limiting factor on land. When sunlight is plentiful and atmospheric temperature climbs, it has been claimed that the phytoplankton of the ocean surface waters may thrive and produce more dimethyl sulfide, DMS. The DMS molecules act as cloud condensation nuclei, which produce more clouds, and thus increase the atmospheric albedo, and this feeds back to lower the temperature of the atmosphere. However, rising sea temperature has stratified the oceans, separating warm, sunlit waters from cool, nutrient-rich waters. Thus, nutrients have become the limiting factor, and plankton levels have actually fallen over the past 50 years, not risen. As scientists discover more about Earth, vast numbers of positive and negative feedback loops are being discovered, that, together, maintain a metastable condition, sometimes within very broad range of environmental conditions. Environmental pressure, such as competition or change in temperature, can lead to adaptation/extinction of species over time.
Reactive[edit]
Example of use: "Reactive homeostasis is an immediate homeostasic response to a challenge such as predation."
However, any homeostasis is impossible without reaction - because homeostasis is and must be a "feedback" phenomenon.
The phrase "reactive homeostasis" is simply short for "reactive compensation reestablishing homeostasis", that is to say, "reestablishing a point of homeostasis." - it should not be confused with a separate kind of homeostasis or a distinct phenomenon from homeostasis; it is simply the compensation (or compensatory) phase of homeostasis.
Other fields[edit]
The term has come to be used in other fields, for example:
Risk[edit]
An actuary may refer to risk homeostasis, where (for example) people that have anti-lock brakes have no better safety record than those without anti-lock brakes, because the former unconsciously compensate for the safer vehicle via less-safe driving habits. Previous to the innovation of anti-lock brakes, certain maneuvers involved minor skids, evoking fear and avoidance: now the anti-lock system moves the boundary for such feedback, and behavior patterns expand into the no-longer punitive area. It has also been suggested[citation needed]that ecological crises are an instance of risk homeostasis in which a particular behavior continues until proven dangerous or dramatic consequences actually occur.
Stress[edit]
Sociologists and psychologists may refer to stress homeostasis, the tendency of a population or an individual to stay at a certain level of stress, often generating artificial stresses if the "natural" level of stress is not enough.[citation needed]
Jean-François Lyotard, a postmodern theorist, has applied this term to societal ‘power centers‘ that he describes as being ‘governed by a principle of homeostasis,‘ for example, the scientific hierarchy, which will sometimes ignore a radical new discovery for years because it destabilises previously accepted norms. (See The Postmodern Condition: A Report on Knowledge by Jean-François Lyotard)
Psychological[edit]
Author George Leonard discusses in his book Mastery how homeostasis affects our behavior and who we are. He states that homeostasis will prevent our body from making drastic changes and maintain stability in our lives even if it is detrimental to us.[13] Examples include when an obese person starts exercising, homeostasis in the body resists the activity to maintain stability.[14] Another example Leonard uses is an unstable family where the father has been a raging alcoholic and suddenly stops and the son starts up a drug habit to maintain stability in the family. Homeostasis is the main factor that stops people changing their habits because our bodies view change as dangerous unless it is very slow. Leonard discusses this dilemma as the media today only encourages fast change and quick results. The opening of his book aptly describes his despair with the current state of the world and how it is at war with homeostasis. "The trouble is that we have few, if any, maps to guide us on the journey or even to show us how to find the path. The modern world, in fact, can be viewed as a prodigious conspiracy against mastery. We‘re continually bombarded with the promises of immediate gratification, instant success, and fast, temporary relief, all of which lead in exactly the wrong direction."外温动物又叫冷血动物,变温动物。体温随着外界温度改变而改变的动物,叫做外温动物;如鱼、蛙、蛇等。外温动物又称冷血动物,地球上的动物大部分都是 冷血动物.冷血动物并不是需要寒冷,而是其体温与其所生活的环境类似,例如蚯蚓的体温等于所住的土壤 的温度;鱼的体温等于其四周的水温.这一类动物的体 温是随著环境温度的改变而改变,所以,以外温动物的专有名词来形容其可变的体温,最能叙述其真义.
2由来
homeostasis稳态